Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0366647
PubChem CID
Molecular Formula
C20H22N8O
Molecular Weight
390.451 g/mol
Synonyms/Alias
[CHEMBL4536665; BDBM50532048]
InChI Key
MQRZGOHLKSFXAK-UHFFFAOYSA-N
InChI
InChI=1S/C20H22N8O/c1-14-10-18(28(24-14)17-8-3-2-4-9-17)22-19(29)13-27-25-20(23-26-27)16-7-5-6-15(11...
IUPAC Name
2-[5-(3-cyanophenyl)tetrazol-2-yl]-N-(2-cyclohexyl-5-methylpyrazol-3-yl)acetamide
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

51 54 0 0 0 0 0 0 0 0999 V2000
-1.0382 -4.1047 2.3393 C 0 0 0 0 0 0 0 0 0 0 0 0
-1.2675 -2.6480 2.1134 C 0 0 0 0 0 0 0 0 0 0 0 0
-2.4708 -2.115...

Experimental Data

Activity Data

Target Ion Channel
ATP sensitive inward rectifier potassium channel 10
Uniprot Accession Number
Function
Blocker
Species
Rattus norvegicus (Rat)
IC50
IC50: 41700 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.3
Holding Potential
Not specified
Temperature
37 °C
Test Method
Flux assay (Thallium ion)
Test Species
Not specified

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
29
Rotatable Bonds
5
logP
2.8606
Complexity
105.6837
TPSA (Ų)
114.31
H-Bond Donors
1
H-Bond Acceptors
8
Ring Count
4
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